Abnormal lipid composition of chylomicrons in broad-β disease (type III hyperlipoproteinemia)
نویسندگان
چکیده
منابع مشابه
The Lipid Composition of Human Plasma Chylomicrons.
The lipid composition of human chylomicrons has been studied using blood collected from normal male volunteers after ingestion of 200 g of butter fat. The concentration of chylomicrons in the blood samples varied widely among 12 subjects but in each case the following lipids were present : triglycerides, diglycerides (probably the 1,2-isomers), monoglycerides, free and esterified cholesterol, t...
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We describe a new phenotype of hyperlipoproteinemia in two members of a family with a high degree of consanguinity. Both have a history of uncontrolled diabetes mellitus without ketoacidosis, and a family history of coronary artery disease at a relatively early age. A high degree of insulin resistance was found. The abnormal lipoprotein(s) has alpha-lipoprotein mobility on cellulose acetate ele...
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Type III hyperlipoproteinemia (HLP) is a genetic disorder characterized by accumulation of remnant lipoproteins in the plasma and development of premature atherosclerosis. Although receptor binding-defective forms of apolipoprotein (apo) E are the common denominator in this disorder, a number of apparent paradoxes concerning its pathogenesis still exist. However, studies in transgenic animals a...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1970
ISSN: 0021-9738
DOI: 10.1172/jci106403